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Description

Collectively, ongoing research on OA and ferroptosis is advancing rapidly, offering a novel perspective on the complex interplay among cartilage degradation, synovial inflammation, and subchondral bone remodeling

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For these reasons, several drugs have been explored for their protective effects in oxidative stress in vitro models and ischemic stroke mouse models (middle cerebral artery occlusion/reperfusion)

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Additionally, it lowered pro-inflammatory cytokines like TNF- and IL-1, showing anti-inflammatory actions

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Trends Endocrinol Metab 30(9):573575 Gao P et al (2023) Pericyte-derived Exosomal miR-210 improves mitochondrial function and inhibits lipid peroxidation in vascular endothelial cells after traumatic spinal cord injury by activating JAK1/STAT3 signaling pathway

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