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The results were disappointing at that time, but once it became possible to measure insulin, researchers documented the so-called incretin effect, whereby insulin secretion is increased by oral ingestion of glucose to a greater extent than with intravenous injection

For reference on how temperature affects these medications, the peptides at room temperature guide and the peptides in fridge shelf life guide cover the science behind biologic medication stability in accessible detail

The Evidence: Primarily studied in animal and in vitro models, showing GLP-1 stimulation and potential appetite-suppressing effects

Adding CJC/Ipa brings injection-site reactions and mild water retention