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When weighed against the financial and health costs of weight regain, including renewed medication courses, worsening metabolic disease, and associated healthcare utilization, the maintenance approach frequently wins on pure economics

Whereas general obesity and central adiposity, in particular, are the primary factors responsible for the development of insulin resistance, postprandial increases in insulin secretion causes a further expansion of the adipose tissue mass, which further worsens insulin resistance

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Healthier on Ro Our members on GLP-1s are losing weight, but that's not the full story