Food and Drug Administration (FDA), the most commonly reported side effects of these medications include nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, indigestion, dizziness, bloating, belching, and flatulence
The average proportion of GLP-1 claims that were rejected rose from 30% before Wegovys launch, to 41% after Mounjaro hit the market, reflecting a change in the underlying access profile of GLP-1s for patients
We're giving you 90 days' notice to figure out what you want to do.'" From 2025 to 2026, 12 million people were on plans that dropped coverage for Zepbound and 12 million had plans that dropped Wegovy, another GLP-1, according to research by GoodRx, a website that helps patients find discounts on prescription drugs
The current generation of GLP-1 receptor agonists includes: Semaglutide (weekly subcutaneous injection or oral formulation) Liraglutide (daily subcutaneous injection) Tirzepatide (dual GLP-1/GIP receptor agonist, weekly subcutaneous injection) Each of these GLP-1 agents carries a distinct pharmacological profile, and the optimal choice depends on a patients clinical history, metabolic risk factors, and therapeutic goals a determination best made in consultation with a physician experienced in metabolic and longevity medicine