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Description

JAMA 325 , 568578 (2021)

This growthhormone then triggers IGF-1 production, which supports protein synthesis,muscle repair, fat metabolism, and tissue recovery

In addition, heterotopic tumors from CreERT2 mice showed diminished inflammation demonstrated by reduced presence of total leukocytes (CD45 + area), TAMs (CD68 + area), neutrophils (MPO + cells), tumor-infiltrating lymphocytes, TILs (FOXP3 + ), as well as T regulatory cells, Tregs (FOXP3 + CD4 + cells)