5 A SeHCAT scan involves swallowing a capsule containing a synthetic bile acid, then having a short scan on the day and again a week later to measure how much has been retained
Pickart 2015 BioMed Res Int sequenced by Affymetrix chip the effects of 10 nM GHK-Cu on human fibroblasts after 24h: 4192 significantly modulated genes, including activation of DNA repair programmes (NBN, BRCA1), regeneration (collagens, elastin, integrins), antioxidant defence (glutathione peroxidase, SOD, peroxiredoxins) and anti-inflammatory modulation (reduction of TNF-alpha, IL-6, IL-8)
the consequences of sustained elevated SAM across cell types are not characterised
(NEJM, 2023) reported constipation in roughly a quarter of participants in the higher-dose arms, though precise per-cohort breakdowns are not published in open summaries [unverified]