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Accumulation of these metabolites and their breakdown products in patients with CKD may be associated with the development of neurotoxicity and uremic breath. 481,487,492

doi: 10.2147/DDDT.S150825 88 LiH

However, HE staining showed slight folding, shrinking and delamination of the basement membrane of seminiferous tubules in the rat testicular tissue, an increasing amount of sperm, insignificant damage to spermatogenesis, a lack of mature spermatogenic cells, a slightly disordered and sparse cell arrangement with 35 layers and visible cell polarity in groups C and D