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Treatment with HM-BPT in a 4T1 xenograft model resulted in significant tumor suppression, infiltration of CTLs, as well as M1 phenotype repolarization and activation of the stimulator of IFN genes (STING) pathway in macrophages [205]

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The most common side effects reported include gastrointestinal symptoms such as nausea, vomiting, and diarrhea, which tend to diminish over time

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