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September 21, 2002

If 8mg weekly produces excellent results with minimal side effects, there may be no benefit to pushing to 12mg if doing so causes substantial discomfort

GLP-1RAs stimulate NO production and eNOS activation, eliciting vasorelaxation in arterial endothelium in vitro [104]

Monitoring Progress and Adjusting Expectations Setting realistic expectations and monitoring progress appropriately helps maintain motivation throughout treatment