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However, because large amounts of fat can worsen nausea or acid reflux in some people taking GLP-1 medications, many people find it more comfortable to include smaller portions throughout the day, such as a drizzle of olive oil on vegetables, a tablespoon of almond butter in a smoothie, a quarter of an avocado with lunch, rather than eating one high-fat meal

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Medium-chain triglycerides (MCTs) consisting of decanoate (C10:0) can improve glucose tolerance and inhibit HFD-induced obesity in mice by stimulating GLP-1 secretion through GPR84 [148]

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