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three daily pills for Orlistat Wegovy causes primarily digestive side effects , while Orlistats main concern is fat malabsorption Cost considerations favor Orlistat, which is available in both prescription and OTC forms Both treatments require lifestyle modifications , including dietary changes and exercise The Semaglutide Treatment Effect in People with obesity (STEP) clinical trial programme is evaluating onceweekly subcutaneous semaglutide 2.4 mg (a glucagonlike peptide1 analogue) in people with overweight or obesity

Results were presented as mean SEM

Some people notice skin tone shifting within 46 weeks