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Following this short course of treatment, the next step was to continue decreasing the inflammation with isotretinoin 10 mg once daily monotherapy, and finally isotretinoin 10 mg once daily with brimonidine 3 mg/g gel on one side of the face to address the background erythema component of the disease

Administration of the CTSB inhibitor CA-074me prior to pancreatitis induction in a rat model significantly reduced intrapancreatic trypsinogen activation

Dezube BJ, Kurzrock R, Eder JP, Supko JG, Meyer CJ, Camacho LH, Andreeff M , Konopleva M, Lescale-Matys L, Hong D

Altered SOD1 maturation and post-translational modification in amyotrophic lateral sclerosis spinal cord