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Stphanie Decollogne for critical reading of the manuscript and Prof

Atractylenolide I can enhance Lactobacillus and Bacteroides , reduces the levels of Escherichia and Candidatus , and by suppressing the TLR4/MyD88/NF-B pathway to reduce IL-1 and LPS levels ( Actinobacteria growth, elevates Bacteroidetes levels (Ren et al., 2021)

The D-Retro-Inverso modification ensures the peptide maintains its binding affinity while resisting proteolytic degradation, allowing extended therapeutic activity for senescent cell targeting in complex tissue environments

Botox is particularly effective against dynamic wrinkles, which are caused by repetitive muscle movements such as laughing, smiling, or squinting