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Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial

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Maiti A, Kantarjian HM, Popat V, Blanco C, Velasquez M, Garcia-Manero G, Konopleva MY, Verstovsek S, Andreeff M , Borthakur G, Kadia TM, Daver NG, Pemmaraju N, DiNardo CD, Pierce S, Wierda W, Kornblau S, Ravandi F, Cortes JE

How This Works Dihexa is a modified dipeptide-like molecule built from the tyrosine-isoleucine core of angiotensin IV , with both termini capped by hexanoic-acid-derived groups that raise lipophilicity and blunt enzymatic degradation the changes that gave it oral activity and blood-brain-barrier penetration [1]