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These include: Nausea, vomiting, and diarrhoea (very common, especially during dose escalation) Reduced appetite and abdominal discomfort Constipation Risk of hypoglycaemia when used with insulin or sulphonylureas Pancreatitis and gallbladder disease have been reported Thyroid C-cell tumours have been observed in animal studies, though the relevance to humans is unknown Important safety considerations when using both treatments include: Mounjaro can reduce the effectiveness of oral contraceptives due to delayed gastric emptying

Oral supplementation almost never produces symptoms because the body absorbs only a small fraction of high-dose oral B12 and excretes the rest

Avoid High-Fat and Spicy Foods : Foods that are high in fat or spicy can make nausea worse

Reduced inflammation and pain relief without surgery