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The stress adaptation ability improved because of the modification of cysteine residues (Supplemental Fig

doi:10.1177/20503121241275467

Principles emerging from compartmentalization Compartmentalization reveals unifying redox principles: microdomains and relays emerge as short-range H 2 O 2 gradients are shaped and transmitted by peroxiredoxin-based cycles, allowing selective oxidation of target cysteines without elevating bulk oxidative stress (Sies 2017)