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The mechanistic consequence is that GHRP-6 activates the full biological program that ghrelin controls not just GH secretion, but somatostatin suppression, appetite signaling via NPY/AgRP pathways, gastric motility, and elements of the reward circuitry

Progesterone levels drop sharply from 10-20 ng/mL to under 1 ng/mL just before your period, reducing the hormone's natural gut-slowing effects and disrupting beneficial bacteria balance