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While recent incretin-based therapies have provided pharmaceutical inroads into treatment of obesity, there remains an ongoing need for additional medicines with distinct modes of action as independent or complementary therapeutics

GLP-1 therapy isnt recommended for teens with certain medical conditions such as a personal or family history of medullary thyroid cancer or MEN2, pancreatitis, severe gastrointestinal issues (like gastroparesis or IBD flare), current or planned pregnancy, or active eating or psychiatric disorders

One-carbon metabolism and prostate cancer risk: Prospective investigation of seven circulating B vitamins and metabolites