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Renal function and volume status should be assessed prior to initiating therapy

But you have to be careful because the significant reduction in calories that can occur alongside of Akito diet and when you're cutting a lot of carbohydrates at the diet can significantly decrease the amount of insulin you're taking in that Lantis and you need to make sure that you're talking to your doctor about that to make sure that you have a plan in place that you do not over dose yourself with insulin and end up having a low blood sugar effect