So far, it has not been possible to develop a treatment based on BDNF, as this growth factor does not cross the bloodbrain barrier (BBB)
38 At week 26, 3 mg, 7 mg, and 14 mg of oral semaglutide significantly reduced HbA1c from baseline by 0.9%, 1.2%, and 1.4%, respectively, compared to 0.3% in the placebo group
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