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We were looking at these rodent studies, and were like, these look really promising. And were doing the math on species conversions to figure out human doses. Nobody was under the illusion that what they were doing was definitively safe, he continued

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In addition, autophagy results in iron-dependent ferroptosis by regulating the induction of TFR1 and degradation of ferritin (Park and Chung, 2019)

A patient may be currently tapering off of their oral steroids and experience a small flare