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doi: 10.1016/S0140-6736(20)30925-9 2 CoronadoFMelvinSCBellRAZhaoG

These trials demonstrated its efficacy and safety in Type 2 diabetes with or without other anti-diabetic agents [42, 44,45,46,47]

If a clinically meaningful increase in heart rate is identified during retatrutide treatment, several management strategies may be considered, depending on the severity of the elevation and the presence of associated symptoms