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Changing patterns in BTMs and BMD are similar to those found in calorie restriction interventions: CTX levels increased to a greater extent compared to those of PINP, and total hip BMD decreased to a greater extent compared to lumbar spine BMD [35, 36]

Medically reviewed by Oghenefejiro Okifo | MD , Harvard Medical School | Henry Ford Hospital - Detroit, MI on June 21st, 2025

Furthermore, Nrf2 overexpression raises the expression levels of FSP1, GPX4, SLC7A11, and other related proteins in lung cancer [114, 115], and obstructs the therapeutic process of ferroptosis activators by shielding lung cancer cells from ferroptosis

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