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If you are comparing the two medications and travel frequently or have unreliable refrigeration, semaglutide's longer room-temperature stability may be a practical advantage worth considering

GLP-1 receptor agonists begin working at a physiological level shortly after administration , but the clinical effects patients notice develop more gradually over days to weeks

The NETs then activate factors XIIa and XIa of the coagulation cascade, which can cause microthrombi and secondary brain ischemia - and considerably secondary damage

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