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As the current development leader, cotadutide has still not been able to escape the spectre of dose-dependent gastrointestinal adverse events (82)

Then, one optrode (16 tungsten wires surrounding a central optic fiber) was unilaterally implanted in the LH (from bregma (mm): AP -1.3, ML 1.0, and from dura: DV -5.5), and a subcutaneous catheter was inserted subcutaneously for tesofensine administration