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The discovered BV levels that inhibit cancer cells may be inadequate to be considered in systemic-therapy without substantial adverse effects

155 Furthermore, GDH-derived NADPH is consumed to support the reductive carboxylation of -KG by IDH2, and the compensatory increase in the expression of GDH1 or GDH2 promote the growth of IDH-mutant glioma cells

Do not use if the medication has been frozen