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[7] Distinctly, topiramate may potentiate central nervous system depression when co-administered with alcohol, opioids, or benzodiazepines, necessitating cautious dose titration and patient education on operating machinery

If it is to help manage chronic weight regain or diabetes, you may need to take it long-term, just as you would with blood pressure medication

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The product information for semaglutide and liraglutide includes warnings about acute pancreatitis (a known, uncommon adverse effect) but does not list pancreatic cancer as an established risk