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Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism

Fewer pipetting steps means fewer opportunities for protocol drift

The divergence in the effect of mutagenesis of residues comprising the TM binding pocket, even where interactions in the static consensus structures were similar, confirmed that static visualisation of complexes is insufficient to fully understand binding and activation mechanisms, and suggests that the dynamics of peptide-receptor engagement likely play a critical role

Beyond convenient home delivery, NovoCare also supports patients with benefit verification, refill reminders, and access to live support from a NovoCare case manager