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In 1978, building on this discovery, Zamecnik and Stephenson 32 used specific oligodeoxynucleotide chains that target the 35S RNA of the Rous sarcoma virus to inhibit virus replication, marking a prototype for the application of antisense oligonucleotide (ASO) drugs in disease treatment

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(2007), other than insulinoma, illustrated that GLP-1R is also high expression in gastrinoma, MTC, 60% of pheochromocytoma, and gastrinoma