The platform for recombinant protein secretion using Usp45 secretion signal and cAcmA surface anchor was used to target TNF, IL-6, IL-8, IL-17, and other cytokines and chemokines, all important players involved in the pathology of inflammatory bowel disease [18, 19]
Together, these three mechanisms span the key stages of the wound healing and tissue regeneration cascade from initial vascular response and inflammation modulation through to matrix remodelling and re-epithelialisation making the Glow Stack a unique tool for multi-pathway tissue biology research
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