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Newer approaches, such as activation of the Takeda G protein-coupled receptor 5 (TGR5
Neurogenic inflammation in acute migraine attacks is characterized by a TVS activation-induced release of neuropeptides, such as CGRP and substance P, from trigeminal nerve fibers at the dura, which causes increased vascular permeability, plasma protein extravasation, leukocyte infiltration, vasodilation, mast cell degranulation, activation of meningeal nociceptors, and the subsequent release of inflammatory mediators (5)
These images can identify rotation or sinking of the coffin bone, monitor healing, and guide trimming or shoeing decisions
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