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A B6-deficient person starting semaglutide faces a double problem: their neurotransmitter synthesis is already compromised, and semaglutide further disrupts the GI and central nervous system pathways that depend on adequate B6 levels

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1.6g x 35g Practical targets by body weight: 150 lbs (68 kg): approximately 82109 grams of protein per day 180 lbs (82 kg): approximately 98131 grams of protein per day 220 lbs (100 kg): approximately 120160 grams of protein per day These targets are challenging to hit when appetite is suppressed

Thats also why the fundamental nature of weight loss calories in, calories out is technically true but fickle in nature