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Your doctor will also consider your medical history, previous weight loss efforts, and whether the benefits of medication outweigh potential risks for you

[DOI] [PubMed] [Google Scholar] 23.Ferreira C.S., Carvalho K.C., Maganhin C.C., Paiotti A.P.R., Oshima C.T.F., Simes M.J., Baracat E.C., Soares J.M

Normal GLP-1 side effects include mild nausea and fullness that typically improve within 48 weeks, while gastroparesis involves persistent symptoms beyond 12 weeks, vomiting of undigested food hours after meals, and severe impairment of nutritional intake requiring objective diagnosis via gastric emptying scintigraphy

Thyroid Safety and Cancer Risk Concerns in Extended Use Animal studies of GLP-1 and GIP agonists revealed dose-dependent thyroid C-cell proliferation and increased risk of medullary thyroid carcinoma in rodents, which led to a black box warning on all GLP-1 medications