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Of course, if an orphan drug is deemed the best course of treatment for a member, this is evaluated in our clinical review process and addressed on a case-by-case basis

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This phenomenon is thought to be due to a natural consequence of rapid weight loss combined with slow elastin turnover, rather than a direct effect of these drugs on adipocytes of the face or buttocks and may resolve with weight gain upon drug cessation (135b)

Studies show that even one skipped dose can trigger a slight increase in food intake within days, potentially leading to 12 pounds of weight gain if you don't actively maintain your eating discipline