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Furthermore, Redox proteomics studies found that many antioxidant enzymes that are allocated in the mitochondria, including glutathione-S-transferase Mu, peroxiredoxin 6, GSH and ATP synthase are oxidized in AD, which might compromise their functions by increasing oxidative stress conditions that prevail in AD affected brain regions (Swomley and Allan Butterfield, 2015)

Sufficient amounts of free carnitine can facilitate the entry of accumulated acyl-CoA into mitochondria, reducing its inhibition of adenine nucleotide translocase, thereby allowing oxidative phosphorylation to proceed smoothly

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Some scars heal well, others remain more visible