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note that lactulose is not recommended as it may worsen bloating [14] [18] For abdominal pain : Antispasmodics (mebeverine, peppermint oil) taken before meals For global symptoms : Tricyclic antidepressants at low doses, with selective serotonin reuptake inhibitors (SSRIs) considered if TCAs are ineffective or not tolerated Psychological therapies have robust evidence in IBS management, including cognitive behavioural therapy (CBT), gut-directed hypnotherapy, and mindfulness-based interventions

Secondly, another potential reason is the presence of mismatches in the core region targeted by HCV 1a-, 1b- and 6-specific primers and probes used by the GT Plus assay

The main application scenarios are as follows

How does removing injection barriers change treatment access