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Thats about equivalent to a roast chicken breast (at 54g protein) and two large eggs (at 6g protein each)
After 72 weeks of treatment: 5 mg dose: 15.0% mean body weight reduction 10 mg dose: 19.5% mean body weight reduction 15 mg dose: 20.9% mean body weight reduction Placebo: 3.1% mean body weight reduction Among participants receiving 15 mg, approximately 57% achieved at least 20% weight loss
Altogether, the data strongly points that even low Rot doses could impair synaptic function
The STEP 1 trial showed semaglutide 2.4 mg led to 14.9% weight loss over 68 weeks, while SURMOUNT-1 showed tirzepatide achieved up to 20.9% weight reductionapproaching bariatric surgery outcomes.[6] The SELECT trial (17,604 patients) found semaglutide reduced cardiovascular death, non-fatal heart attack, and non-fatal stroke by 20% and all-cause mortality by 19%, suggesting direct cardioprotective effects beyond weight loss.[4] In STEP-HFpEF, semaglutide produced 13.3% weight loss in heart failure patients and improved symptoms and physical function
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