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The COR-I trial, involving 1,742 participants over 56 weeks, demonstrated 6.1% average weight loss with Contrave versus 1.3% with placebo (Greenway et al., Obesity, 2010)

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But, in spite of their numerous favorable effects is unfortunately not suitable for the practical preparation of medicine for several reasons: from gastric juice is not possible produce the required amount the compound BPC with constant quality