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Phosphodiesterase 10A inhibition improves cortico-basal ganglia function in Huntingtons disease models
Individual response varies widely
As a supplement derived from the amino acid cysteine, NAC is believed to support glutathione production
Our identification of VRK2-mediated SLC7A11 trafficking suggests a potential immune evasion mechanism, as SLC7A11-high tumors often display T cell exclusion phenotypes [37], warranting future investigation into whether VRK2 expression could predict therapeutic response to combined ferroptosis inducers and immune checkpoint inhibitors
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