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Also, single-nucleotide polymorphisms in meningioma-expressed antigen 5 (MGEA5), a human OGA homolog, were associated with T2DM onset in Pima Indians and Mexican Americans [72,73]

Exp Mol Med 38:217229

Both processes ensure the regeneration of cytosolic NAD + to sustain glycolysis and maintain energy production 3

They can act as oncogenes (termed OncomiRs) when their overexpression leads to the downregulation of tumor suppressor genes, or they can function as tumor suppressors (TS-miRs) when their loss or downregulation results in the increased expression of oncogenes [33]