The research simply does not exist yet
doi: 10.1016/j.jad.2019.11.122CrossRefGoogle ScholarPubMed Bersani, G., Meco, G., Denaro, A., Liberati, D., Colletti, C., Nicolai, R., Koverech, A

Peptide structure and stability What peptides are: Chains of amino acids Held together by peptide bonds Specific 3D structure required for function Fragile molecules compared to small molecule drugs Why peptides are unstable: Peptide bonds susceptible to hydrolysis (water breaks bonds) Oxidation damages certain amino acids Temperature accelerates degradation Light exposure causes photo-degradation pH changes denature structure Bacterial contamination introduces enzymes that break peptides Degradation mechanisms: Temperature's exponential effect: Every 10C temperature increase roughly doubles degradation rate Room temperature (25C): Rapid degradation (days) Refrigerated (2-8C): Slow degradation (weeks-months) Frozen (-20C): Very slow degradation (years) Ultra-frozen (-80C): Minimal degradation (5+ years) Learn peptide fundamentals at SeekPeptides - explore what are peptides , how peptides work , and getting started with peptides

I know quite a few derms are out there speaking out on this exact topic, saying the marketing is wrong.