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Similarly, a remarkable kinase modulator effect was observed in several studies, mostly by reducing phosphorylation levels of ERK, BRAF and AKT [64, 99, 109, 122, 123] (Figs

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When NRF-2 is exposed to inflammation or oxidative stress (OS), it phosphorylates and translocates into the nucleus, giving rise to the transcription of proteins and antioxidant enzymes [7]

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