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on 24 patients with generalized vitiligo and 20 healthy controls found statistically significant higher levels of superoxide dismutase activity in erythrocytes, serum MDA, and nitric oxide (NO) and statistically significant lower levels of glutathione and glutathione peroxidase in the patients of vitiligo compared to the controls.[] Secondary to the oxidative stress, the polyunsaturated fatty acids undergo peroxidation resulting in formation of free radicals

Mller T, Woitalla D, Hauptmann B, Fowler B, Kuhn W (2001) Decrease of methionine and S-adenosylmethionine and increase of Homocysteine in treated patients with Parkinsons disease

The daily injection requirement deters some patients but provides steady levels without the peaks and troughs of weekly dosing

Designed for daily use, it cleanses the skin while providing targeted treatment for pigmentation issues