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The question that matters clinically is whether a given patient is a good candidate, what the right protocol looks like for their specific goals and lab results, and whether they have access to a supervised framework that can catch the small number of patients for whom these compounds are not appropriate before they start rather than after

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Where it earns its dark spot name, though, is with ingredients that go beyond all-over glow: Niacinamide helps block pigment transfer, while licorice root extract fades discoloration and calms inflammation that can lead to post-acne marks

Others find restarting therapy less tolerable, with increased side effects like nausea or gastrointestinal discomfort