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Introduction# CagriSema and retatrutide represent two of the most anticipated next-generation obesity treatments, each taking a fundamentally different multi-target approach to weight management

European Journal of Anaesthesiology, 18 , 419-422

Tesofensine (2 mg/kg, subcutaneously) and Clozapine-N-Oxide (CNO, 3 mg/kg, intraperitoneally), both drugs or vehicle (DMSO or saline) were administered at 18:30 (30 minutes before the dark cycle begins)