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The results achieved are as follows: 19 percent fat reduction of fat in three months, 23 percent in six months 4 cm (1.5 inches) reduction in waist 16 percent increase in muscle mass achieved in one month, 19 percent at three months, and 18 percent in six months

2,3 In a Phase I multiple-dose clinical trial conducted in healthy adults, pharmacokinetics were dose-proportional, accompanied by reductions in both fasting and oral glucose tolerance glucose levels

The goal of the study was to ascertain whether GI adverse events (GI AEs), such as nausea/vomiting, diarrhea, constipation, and dyspepsia (indigestion), during the dose escalation phase (baseline to week 12) and from baseline to the end of treatment, are responsible for the greater weight loss seen with semaglutide compared to other GLP-1RAs

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