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These symptoms indicate local inflammation but are not dangerous

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Overall, there were significant changes in existing symptoms (i.e., fatigue, pain, insomnia, constipation), while paresthesia, diarrhea, and nausea emerged as new or worsening symptoms over time

DL: As we look to the future, we intend to measure new populations that include a mix of GLP-1s that have come to market since the initial study time period