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[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Locally renewing resident synovial macrophages provide a protective barrier for the joint

The FDA has approved Wegovy (semaglutide 2.4 mg) and Zepbound (tirzepatide) for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

& Rodrguez, L

The SURMOUNT trials showed tirzepatide at 15 mg achieving 15% to 21% weight loss by week 72, compared to semaglutide at 2.4 mg achieving approximately 15% by week 68