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These hydrophobic regions attract each other, causing multiple denatured peptides to clump together into insoluble aggregates

10.1007/s11120-005-8425-1 30 MicheletL.ZaffagniniM.MarchandC.CollinV.DecottigniesP.TsanP.et al

Thats because traditional anti-aging approaches treat the visible signs without addressing whats driving aging at the cellular level

In contrast, the prolyl isomerase cyclophilin D in the mitochondrial matrix is an essential regulator of MPT and the only genetically proven indispensable MPT component (Nakagawa et al., 2005