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The effects of 3 weeks of oral glutathione supplementation on whole body insulin sensitivity in obese males with and without type 2 diabetes : A randomized trial", Applied Physiology, Nutrition, and Metabolism = Physiologie Applique, Nutrition Et Metabolisme, 46 (9), 1133-1142

These investigations, summarized in Table 1, reveal a pleiotropic mechanism of action that extends significantly beyond its metabolic origins ( TABLE 1 Summary of key preclinical studies on semaglutide in neurological models

The primary pathway increases cyclic AMP (cAMP), a molecule that serves as a secondary messenger amplifying the original GLP-1 signal throughout the cell

However, the significance of these findings is difficult to assess without a control group for comparison